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<i>Huperzia javanica<_i> (Sw.) C. Y. Yang

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (3) Bcl-2 Family (1) Cholinesterase (ChE) (6) iGluR (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (1) Parasite (4) STAT (1) TMV (1)
By Research Areas:	Cancer (8) Infection (5) Metabolic Disease (1) Neurological Disease (6)

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Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7190

Yadanzioside F	Parasite	Cancer
Yadanzioside F is one of the toxic components found in Brucea javanica . Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties .

HY-N4257

Yadanzioside A	Others	Cancer
Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity .

HY-127001

Lycodine	Cholinesterase (ChE)	Neurological Disease
Lycodine is a lycopodium alkaloid, which can be isolated from Huperzia saururus. Lycodine exhibits anticholinesterase activity .

HY-125067

Yadanzioside P	Others	Cancer
Yadanzioside P is an antileukemic quassinoid glycoside. Yadanzioside P can be isolated from the seeds of Brucea javanica (L.). Yadanzioside P can be used for the research of cancer .

HY-N10899

Bruceine J	Parasite	Infection
Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity .

HY-N10900

Bruceine C	Parasite	Infection
Bruceine C, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine C has anti-Babesial activity .

HY-N8084

Epimedin B1	Others	Others
Epimedin B1 is initially isolated from E. Wushanense and is a Chemical marker of E. sagittatum in agent Yin-Yang-Huo. Epimedin B1 is the isomer of Epimedin B .

HY-N1279

Semialactone	Others	Others
Semialactone is a triterpenes, which can be isolated from Rhus javanica .

HY-135421

Dehydrobruceantinol	Others	Others
Dehydrobruceantinol is a natural product that can be isolated from Brucea javanica .

HY-N7191

Yadanzioside G	Others	Others
Yadanzioside G is a glucoside that can be isolated from Brucu javanica .

HY-N10897

Bruceantinol A	Others	Others
Bruceantinol A, a natural compound, can be isolated from Brucea javanica seeds .

HY-123083

Javanicin C	Others	Others
Javanicin C is a quassinoid that can be isolated from the bark of Picrasma javanica .

HY-N9027

Bruceantinoside A	Others	Others
Bruceantinoside A is a Diterpenoids product that can be isolated from the fruits of Brucea javanica. .

HY-N2043

Huperzine B	Cholinesterase (ChE)	Neurological Disease
Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Parasite Antibiotic	Infection
Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.

HY-N1299

Shizukanolide C 13-Deoxyshizukanolide F; Deacetylchloranthalactone C	Others	Others
Shizukanolide C (13-Deoxyshizukanolide F) is a Diterpenoids product that can be isolated from the fruits of Brucea javanica. .

HY-122957

Huperzine C	Cholinesterase (ChE)	Neurological Disease
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC₅₀ of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease .

HY-111806

3,7,4'-Trihydroxyflavone 5-Deoxykampferol	Others	Others
3,7,4'-Trihydroxyflavone, isolated from Rhus javanica var. roxburghiana, is a flavonoid with DNA strand-scission activity .

HY-138213

Afzelechin-(4α→8)-epiafzelechin	Others	Others
Afzelechin-(4α→8)-epiafzelechin is a Flavonoids product that can be isolated from the herbs of Cassia javanica .

HY-N2043R

Huperzine B (Standard)	Cholinesterase (ChE)	Neurological Disease
Huperzine B (Standard) is the analytical standard of Huperzine B. This product is intended for research and analytical applications. Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .

HY-N4210

Yadanziolide A	TMV	Infection Cancer
Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC₅₀ of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .

HY-N0840

Bruceantin 1 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	Others	Cancer
Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.

HY-N3015

Bruceine E	Others	Metabolic Disease
Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .

HY-17387

(-)-Huperzine A 4 Publications Verification Huperzine A	Cholinesterase (ChE) Apoptosis iGluR	Neurological Disease
(-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .

HY-N10313

Dehydrobruceine B	Bcl-2 Family Keap1-Nrf2 Apoptosis	Cancer
Dehydrobruceine B, a quassinoid, can be isolated from Brucea javanica. Dehydrobruceine B shows a synergistic effect with Cisplatin (HY-17394) to induce apoptosis via mitochondrial method. Dehydrobruceine B increases apoptosis-inducing factor (AIF) and Bax expression and suppresses Keap1-Nrf2 .

HY-17387S1

(-)-Huperzine A-d4 hydrochloride Huperzine A-d₄	iGluR Cholinesterase (ChE) Apoptosis Isotope-Labeled Compounds	Neurological Disease
(-)-Huperzine A-d₄ hydrochloride is deuterated labeled (-)-Huperzine A (HY-17387). (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .

HY-N8146

Bruceantinol	STAT	Infection Cancer
Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper . Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC₅₀=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc .

HY-N10591

Bruceantarin	Others	Cancer
Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7190

Yadanzioside F	Structural Classification Simaroubaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	Parasite
Yadanzioside F is one of the toxic components found in Brucea javanica . Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties .

HY-N4257

Yadanzioside A	Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	Others
Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity .

HY-127001

Lycodine	Lycopodiaceae Structural Classification Alkaloids Huperzia miyoshiana (Makino) Ching Source classification Pyridine Alkaloids Plants	Cholinesterase (ChE)
Lycodine is a lycopodium alkaloid, which can be isolated from Huperzia saururus. Lycodine exhibits anticholinesterase activity .

HY-125067

Yadanzioside P	Structural Classification Simaroubaceae Source classification Plants Saccharides Monosaccharides Brucea javanica (L.) Merr.	Others
Yadanzioside P is an antileukemic quassinoid glycoside. Yadanzioside P can be isolated from the seeds of Brucea javanica (L.). Yadanzioside P can be used for the research of cancer .

HY-N10899

Bruceine J	Structural Classification Simaroubaceae Terpenoids Source classification Diterpenoids Plants Brucea javanica (L.) Merr.	Parasite
Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity .

HY-N10900

Bruceine C	Structural Classification Simaroubaceae Terpenoids Source classification Diterpenoids Plants Brucea javanica (L.) Merr.	Parasite
Bruceine C, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine C has anti-Babesial activity .

HY-N8084

Epimedin B1	Flavonols Structural Classification Monophenols Flavonoids Classification of Application Fields Source classification Other Diseases Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields	Others
Epimedin B1 is initially isolated from E. Wushanense and is a Chemical marker of E. sagittatum in agent Yin-Yang-Huo. Epimedin B1 is the isomer of Epimedin B .

HY-N1279

Semialactone	Triterpenes Structural Classification Simaroubaceae Terpenoids Source classification Plants Brucea javanica (L.) Merr.	Others
Semialactone is a triterpenes, which can be isolated from Rhus javanica .

HY-135421

Dehydrobruceantinol	Triterpenes Structural Classification Simaroubaceae Terpenoids Source classification Plants Brucea javanica (L.) Merr.	Others
Dehydrobruceantinol is a natural product that can be isolated from Brucea javanica .

HY-N7191

Yadanzioside G	Structural Classification Natural Products Simaroubaceae Source classification Plants Saccharides Monosaccharides Brucea javanica (L.) Merr.	Others
Yadanzioside G is a glucoside that can be isolated from Brucu javanica .

HY-N10897

Bruceantinol A	Structural Classification Simaroubaceae Terpenoids Source classification Diterpenoids Plants Brucea javanica (L.) Merr.	Others
Bruceantinol A, a natural compound, can be isolated from Brucea javanica seeds .

HY-123083

Javanicin C	Structural Classification Natural Products Simaroubaceae Source classification Plants Picrasma chinensis P. Y. Chen	Others
Javanicin C is a quassinoid that can be isolated from the bark of Picrasma javanica .

HY-N9027

Bruceantinoside A	Structural Classification Simaroubaceae Terpenoids Source classification Diterpenoids Plants Brucea javanica (L.) Merr.	Others
Bruceantinoside A is a Diterpenoids product that can be isolated from the fruits of Brucea javanica. .

HY-N2043

Huperzine B	Lycopodiaceae Alkaloids Piperidine Alkaloids Lycopodium serratum Thunb． Source classification Pyridine Alkaloids Plants	Cholinesterase (ChE)
Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Infection Triterpenes Simaroubaceae Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Brucea javanica (L.) Merr.	Parasite Antibiotic
Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.

HY-N1299

Shizukanolide C 13-Deoxyshizukanolide F; Deacetylchloranthalactone C	Structural Classification Chloranthus serratus (Thunb.) Roem. et Schult. Terpenoids Sesquiterpenes Source classification Chloranthaceae Plants	Others
Shizukanolide C (13-Deoxyshizukanolide F) is a Diterpenoids product that can be isolated from the fruits of Brucea javanica. .

HY-122957

Huperzine C	Lycopodiaceae Alkaloids Lycopodium serratum Thunb． Source classification Plants	Cholinesterase (ChE)
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC₅₀ of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease .

HY-111806

3,7,4'-Trihydroxyflavone 5-Deoxykampferol	Flavonols Structural Classification Classification of Application Fields Rhus chinensis Mill. Source classification Plants Flavonoids Simaroubaceae Other Diseases Phenols Polyphenols Disease Research Fields Anacardiaceae Brucea javanica (L.) Merr.	Others
3,7,4'-Trihydroxyflavone, isolated from Rhus javanica var. roxburghiana, is a flavonoid with DNA strand-scission activity .

HY-138213

Afzelechin-(4α→8)-epiafzelechin	Structural Classification Flavonoids Leguminosae Source classification Cassia Cassia javanica L. Plants Other Flavonoids	Others
Afzelechin-(4α→8)-epiafzelechin is a Flavonoids product that can be isolated from the herbs of Cassia javanica .

HY-N2043R

Huperzine B (Standard)	Lycopodiaceae Alkaloids Piperidine Alkaloids Structural Classification Lycopodium serratum Thunb． Source classification Pyridine Alkaloids Plants	Cholinesterase (ChE)
Huperzine B (Standard) is the analytical standard of Huperzine B. This product is intended for research and analytical applications. Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .

HY-N4210

Yadanziolide A	Infection Structural Classification Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.	TMV
Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC₅₀ of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .

HY-N0840

Bruceantin 1 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Source classification Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	Others
Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.

HY-N3015

Bruceine E	Structural Classification Simaroubaceae Classification of Application Fields Terpenoids Source classification Metabolic Disease Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.	Others
Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .

HY-17387

(-)-Huperzine A 4 Publications Verification Huperzine A	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Anti-aging Terpenoids Huperziaceae Sesquiterpenes Pyridine Alkaloids Huperzia serrata Plants Disease Research Fields	Cholinesterase (ChE) Apoptosis iGluR
(-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .

HY-N10313

Dehydrobruceine B	Structural Classification Natural Products Microorganisms Source classification	Bcl-2 Family Keap1-Nrf2 Apoptosis
Dehydrobruceine B, a quassinoid, can be isolated from Brucea javanica. Dehydrobruceine B shows a synergistic effect with Cisplatin (HY-17394) to induce apoptosis via mitochondrial method. Dehydrobruceine B increases apoptosis-inducing factor (AIF) and Bax expression and suppresses Keap1-Nrf2 .

HY-N8146

Bruceantinol	Infection Triterpenes Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Source classification Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	STAT
Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper . Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC₅₀=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc .

HY-N10591

Bruceantarin	Structural Classification Natural Products Simaroubaceae Plants Brucea javanica (L.) Merr.	Others
Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research .

Cat. No.	Compare	Product Name	Species	Source

HY-P71136

	YY1 Protein, Human (His) 1 Publications Verification Transcriptional repressor protein YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and Yang 1; INO80S	Human	E. coli
	The multifunctional transcription factor YY1 controls a variety of cellular and viral genes by binding to sites that overlap with the transcription start site. YY1 recognizes the consensus sequence 5'-CCGCCATNTT-3' and exhibits context-dependent transcriptional regulation, with methylation of the initial CG dinucleotide affecting binding affinity. YY1 Protein, Human (His) is the recombinant human-derived YY1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of YY1 Protein, Human (His) is 101 a.a., with molecular weight of 17-20 kDa.

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HY-17387S1

(-)-Huperzine A-d4 hydrochloride

(-)-Huperzine A-d₄ hydrochloride is deuterated labeled (-)-Huperzine A (HY-17387). (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .

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HY-P82701

	YY1 Antibody (YA2446) YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and Yang 1; YY-1	WB, IP	Human, Mouse, Rat
	YY1 Antibody (YA2446) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2446), targeting YY1, with a predicted molecular weight of 45 kDa (observed band size: 65 kDa). YY1 Antibody (YA2446) can be used for WB, IP experiment in human, mouse, rat background.

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<i>Huperzia javanica<_i> (Sw.) C. Y. Yang

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products